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This is the evidence view. Different line colors represent the types of evidence for the association.

 
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Your Input:
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A); Involved in cell cycle checkpoint enforcement. Can interact and phosphorylate BUB3 (1087 aa)
(Homo sapiens)
Predicted Functional Partners:
BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (hBUBR1) (MAD3/BUB1- [...] (1050 aa)
    0.999
BUB3
Mitotic checkpoint protein BUB3; Required for kinetochore localization of BUB1 (328 aa)
     0.999
CDC20
Cell division cycle protein 20 homolog (p55CDC); Required for full ubiquitin ligase activity of [...] (499 aa)
     0.999
PLK1
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threon [...] (603 aa)
     0.998
ZW10
Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, whi [...] (779 aa)
     0.986
SGOL1
Shugoshin-like 1 (hSgo1) (Serologically defined breast cancer antigen NY-BR-85); Plays a centra [...] (561 aa)
      0.982
SGOL2
Shugoshin-like 2 (Tripin); Plays a central role in chromosome cohesion during cell division by [...] (1265 aa)
      0.980
CDC2
Cell division control protein 2 homolog (EC 2.7.11.22) (EC 2.7.11.23) (p34 protein kinase) (Cyc [...] (297 aa)
     0.977
NDC80
Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cance [...] (642 aa)
      0.972
RPS27
40S ribosomal protein S27 (Metallopan-stimulin 1) (MPS-1) (84 aa)
      0.971
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
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additional (white) nodes         or: network depth
       

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